Iron Bisglycinate

• Provides a clinical dose of 45 mg of elemental iron per capsule.
  
• The highly absorbable form, iron bisglycinate chelate, has superior bioavailability compared to standard forms.
  
• Comparable to ferrous sulfate at ¼ to ½ the same dose of elemental iron
  
• Iron bisglycinate chelate is significantly better tolerated than commonly used forms, allowing for continued use and improved effectiveness in replenishing iron stores.
  
• Suitable for vegetarians and vegans

Iron deficiency remains the most widespread nutrient deficiency and the most common cause of anemia worldwide. Depleted iron stores impair mitochondrial function and cellular respiration even in the absence of anemia, particularly in metabolically active cells, contributing to the onset of symptoms ranging from fatigue and exercise intolerance to cognitive and cardiac disorders. In the majority of cases, the primary means of replenishing iron levels is oral iron supplementation, which is preferable to parenteral administration (injections) in the absence of severe symptoms or contraindications.

In contrast, iron bisglycinate chelate, composed of two glycine molecules chelated to ferrous iron (Fe2+), has demonstrated significantly superior bioavailability compared to standard iron forms such as ferrous sulfate, ferrous fumarate, and iron polymaltose. This form is much better tolerated, allowing for effective restoration of iron levels using lower doses. For example, at ¼ to ½ the dose of ferrous sulfate, iron bisglycinate chelate has shown similar effects on hemoglobin, ferritin, and other markers of hematological status in controlled trials, with better tolerability. It has also proven effective and well-tolerated in various patient populations, including pregnant women and children with celiac disease. 45 mg of elemental iron per capsule, higher than most formulations, is in line with current recommendations for restoring depleted iron levels in pregnant women, although below the threshold generally associated with adverse effects.

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