• Combines three forms of vitamin B12
• Features three forms of vitamin B12: hydroxycobalamin, adenosylcobalamin, and methylcobalamin
• High dose of bioavailable and active forms of vitamin B12
• Sourced cleanly from Europe

AOR's Tri B12 Synergy is a combination of three active and independent forms of vitamin B12. Methylcobalamin, hydroxycobalamin, and adenosylcobalamin are three distinct cobalamin factors, each with its own specific benefits. Together, they provide an appropriate dose of bioavailable and active forms of B12 for comprehensive support in addressing deficiency. Vitamin B12 deficiency can result from poor diet, altered gut flora, or malabsorption caused by conditions like Crohn's disease or celiac disease, or the use of proton pump inhibitors such as antacids. At-risk populations include the elderly, vegans, and smokers. Chronic antibiotic use and even genetic factors can also increase risk.

Vitamin B12 is used as a cofactor in enzymatic processes that facilitate reactions in the body, much like a key starts a car. Each form of cobalamin – methyl-, hydroxyl-, adenosyl- – is vital for different cellular processes. In their absence, key physiological processes are compromised; B12 deficiency can cause a variety of symptoms over time, from fatigue to increased cardiovascular risk, poor balance, cognitive changes, or depression.

Methylcobalamin is involved in the critical metabolic process called methylation, as well as in red blood cell production, neurotransmitter and DNA synthesis, and the recycling of homocysteine, which is important for heart health.

Adenosylcobalamin works within the mitochondria (the cell's powerhouses) to support metabolic function, including carbohydrate and lipid metabolism, energy production, and for maintaining nervous system health.

Hydroxycobalamin acts as a precursor to the two forms mentioned above and has independent detoxifying actions. It is also bound to the body's transport molecules and serves as a storage form for later conversion, thus ensuring a more sustained supply.

AOR presents vitamin B12 in its three most active and bioavailable forms. AOR sources ingredients from European suppliers certified to "Green Chemistry" system standards.