• Supports energy production, nutrient metabolism, liver function, immune function, and red blood cell formation.
• Contributes to the health of hair, skin, and nails
• Contains a full spectrum of B vitamins in their most metabolically active forms, which do not require liver conversion for use.
• Provides a clinically effective dose of the most active and bioavailable form of folate, Quatrefolic.
• Each capsule also provides the most bioactive and bioavailable forms of each B vitamin, including methylcobalamin (B12), riboflavin 5'-phosphate (B2), and pyridoxal 5'-phosphate (B6).
• Suitable for vegetarians and vegans

Bioclinic Naturals Enhanced B Complex is a once-daily formula that provides a full spectrum of B vitamins in their most metabolically active forms. B vitamins are cofactors for many important mechanisms in the body, including nutrient metabolism, energy production, growth and development, and liver function. B vitamins also contribute to immunity, red blood cell formation, and iron metabolism, as well as the health of skin, hair, and nails. This formula contains B vitamins in their active forms, such as B12 (methylcobalamin) and B6 (pyridoxal 5'-phosphate), to support nervous system function. It also contains 50 mg of choline and 400 mcg of folate (Quatrefolic). Additionally, this formula includes B1, B2, B5, and B6 vitamins, along with niacin, with the added support of biotin and inositol. This convenient all-in-one B complex is an ideal supplement to help support metabolism, energy, and overall health.

Quatrefolic is an active form of folate at the cellular level, the form found in circulation and the only one to cross the blood-brain barrier. It may also be the optimal form for preventing neural tube defects. It does not need to be converted into its active form by the methylenetetrahydrofolate reductase (MTHFR) enzyme, which is known to have common single nucleotide polymorphisms. Administration of quatrefolic acid has been associated with higher peak levels of (6S)-5-MTHF than folic acid and 5-MTHF calcium, even in individuals with high-functioning MTHFR polymorphisms.

Methylcobalamin is a cofactor for B12-dependent enzymes and has direct biological activity. When combined with other B vitamins, it reduces the risk of macular degeneration and migraines, with efficacy sometimes modulated by MTHFR status.